PRMT5 function and targeting in cancer

Protein methyl transferases play critical roles in numerous regulatory pathways that underlie cancer development, progression and therapy-response.Here we discuss the function of PRMT5, a member of the nine-member PRMT family, in controlling oncogenic processes including tumor intrinsic, ALKALINE PITCHER FILTER 3PACK as well as extrinsic microenvir

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Selective Laser Melting of Free-Assembled Stainless Steel 316L Hinges: Optimization of Volumetric Laser Energy Density and Joint Clearance

Selective laser melting technology is one of the metal additive manufacturing technologies that can convert metal powder to complex Gun Slips parts without the assembly process.This study aims to optimize the volumetric laser energy density for printing 3D metal objects with hinges geometry.The material is stainless steel 316L powder.The volumetric

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Electric field stimulation directs target-specific axon regeneration and partial restoration of vision after optic nerve crush injury.

Failure of central nervous system (CNS) axons to regenerate after injury results in permanent Tea disability.Several molecular neuro-protective and neuro-regenerative strategies have been proposed as potential treatments but do not provide the directional cues needed to direct target-specific axon regeneration.Here, we demonstrate that applying an

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